Publications by authors named "Jhean Gabriel Gonzales Yovera"

Hepatocrinology explores the intricate relationship between liver function and the endocrine system. Chronic liver diseases such as liver cirrhosis can cause endocrine disorders due to toxin accumulation and protein synthesis disruption. Despite its importance, assessing endocrine issues in cirrhotic patients is frequently neglected.

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This review provides an update on the epidemiology, pathophysiology, symptoms, diagnosis and treatment of neuroendocrine neoplasms (NENs) of the small bowel (SB). These NENs are defined as a group of neoplasms deriving from neuroendocrine cells. NENs are currently the most common primary tumors of the SB, mainly involving the ileum, making the SB the most frequently affected part of the gastrointestinal tract.

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Article Synopsis
  • PTID accounts for around 5% of primary gastrointestinal tumors, with varying histological types showing both benign and malignant characteristics.
  • A study analyzed 45 patients, primarily diagnosed at an average age of 54.2 years, with most cases (86%) found in the jejunum; GISTs, lymphomas, and adenocarcinomas were the most common tumor types identified.
  • Double-balloon enteroscopy served as the primary diagnostic and treatment method, supporting various endoscopic procedures for managing these tumors, including biopsies and surgical interventions.
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This article is an extensive review that provides an update on the pathophysiology, symptoms, diagnosis, and treatment of diabetic gastroenteropathy. There is no reported prevalence, but it has been described that patients with type 1 diabetes have a cumulative incidence at 10 years of 5.2%, and type 2 patients, 1%.

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Colorectal cancer (CRC) is the third most frequent cancer in the world and the second cause of death of neoplastic origin. Synchronism in CCR is approximately 3-6%. The gastrointestinal tract is the most frequent place where neuroendocrine neoplasms (NNE) settle and a special type of these neuroendocrine carcinomas (CNE) are rare.

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Article Synopsis
  • - Crohn's disease (CD) is a serious, long-lasting inflammation of the digestive system that is becoming more common in Latin America, severely affecting patients' quality of life.
  • - A study at a major hospital in Lima, Peru, analyzed 55 CD patients, revealing that the average age of diagnosis was about 56 years, with common symptoms including abdominal pain and weight loss.
  • - Key findings included a mix of disease locations and types, predominantly treated with corticosteroids and anti-TNF therapies; about one-third of patients required surgery, and there was a 5.4% mortality rate in the cohort.
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The direct relation between the overweight/obesity, MAFLD and the severity SARS-CoV-2 infection. increase number of cases of obesity and MAFLD is an important risk factor for high mortality of COVID-19 patients.

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