Publications by authors named "Jesus Villar-del Moral"

: Thyroglobulin (Tg) is the specific tumor marker for epithelial thyroid cancer. It holds significant value in the postoperative period, and somehow, the goal of surgery in papillary thyroid cancer (PTC) undergoing total thyroidectomy is to achieve undetectable levels of postoperative thyroglobulin (uTg). : This is a retrospective single-center study in which first basal Tg values were evaluated post-surgery in PTC patients undergoing total thyroidectomy.

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Background: Liver grafts from donation after circulatory death (DCD) are associated with a higher risk of early graft dysfunction, determined by the warm ischemia and cold ischemia times. It is essential to have precise criteria to identify this complication in order to guide therapeutic strategies.

Aim: To validate different graft and recipient survival scores in patients undergoing liver transplantation (LT) with DCD grafts.

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Background: During follow-up, incisional hernias can reduce the quality of life of transplant recipients. The objective was to analyze the incidence of incisional hernia and risk factors to detect improvements.

Methods: Retrospective study of transplant recipients between 2002 and 2021.

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Article Synopsis
  • A study surveyed Spanish endocrine surgeons about their use of intraoperative neural monitoring (IONM) in surgeries, with a focus on thyroid and parathyroid procedures.
  • Results showed that while 75% of respondents used intermittent IONM, only 32% routinely performed preoperative laryngoscopy, indicating varied practices.
  • The main barriers to IONM use included its availability, cost, and perceived lack of value, suggesting that standardized guidelines for IONM application in surgery are still needed.
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Several studies have suggested that single nucleotide polymorphisms (SNPs) related to vitamin D metabolism may affect CRC carcinogenesis and survival. The aim of this study was to evaluate the influence of 13 SNPs involved in the vitamin D metabolic pathway on CRC survival. We conducted an observational retrospective cohort study, which included 127 Caucasian CRC patient from the south of Spain.

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Unlabelled: Controversy surrounds the suitability of simultaneous liver-kidney transplant (SLKT) when compared with sequential transplant. Pretransplant renal failure is a post-transplant mortality predictor, and studies demonstrate worse functioning and lower survival of the renal graft when compared with kidney transplant alone (KTA).

Background: This study compares renal function in patients with SLKT and those who received the contralateral kidney from the same donor.

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Article Synopsis
  • The study analyzed the impact of new direct-acting antivirals (DAA) on liver transplantation (LT) for patients with hepatitis C virus (HCV) from January 2016 to August 2020.
  • Out of 156 LTs, 33 (22%) were for HCV-infected patients, showing a 16% decrease compared to previous treatments with interferon/ribavirin, and the majority were due to hepatocellular carcinoma (HCC) rather than decompensated cirrhosis (DC).
  • After DAA treatment, patients achieved a sustained viral response, with no significant differences in survival rates or post-surgery complications between the groups, indicating the need for further research with
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Postmortem normothermic regional perfusion (NRP) is a rising preservation strategy in controlled donation after circulatory determination of death (cDCD). Herein, we present results for cDCD liver transplants performed in Spain 2012-2019, with outcomes evaluated through December 31, 2020. Results were analyzed retrospectively and according to recovery technique (abdominal NRP [A-NRP] or standard rapid recovery [SRR]).

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Background: Currently, both the American Thyroid Association and the European Thyroid Association recommend preoperative preparation with Lugol's Solution (LS) for patients undergoing thyroidectomy for Graves' Disease (GD), but their recommendations are based on low-quality evidence. The LIGRADIS trial aims to provide evidence either to support or refute the systematic use of LS in euthyroid patients undergoing thyroidectomy for GD.

Methods: A multicenter randomized controlled trial will be performed.

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Background: Focused parathyroidectomy is a safe technique for the treatment of primary hyperparathyroidism. The CaPTHUS score and the Wisconsin index are preoperative diagnostic tools designed to distinguish between single- and multigland disease. The aim of the study is to evaluate the usefulness of these models for predicting multiglandular disease in a European population.

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Purpose: The COVID-19 pandemic brought unprecedented conditions for overall health care systems by restricting resources for non-COVID-19 patients. As the burden of the disease escalates, routine elective surgeries are being cancelled. The aim of this paper was to provide a guideline for management of endocrine surgical disorders during a pandemic.

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Background: Hypocalcaemia is the most frequent complication after total thyroidectomy. Finding a method for its early detection has become a priority. A single-center prospective cohort study was conducted to identify risk factors for postoperative hypocalcaemia, develop an early detection model, and test its validity in a different group of patients.

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Introduction: Venous thromboembolism (VTE) represents a serious postoperative complication that can be prevented by adequate thromboprophylaxis. Surveys provide relevant information about clinician's attitudes and preferences regarding VTE prophylaxis.

Methods: Transversal, descriptive study based on a survey sent to general surgeons members of the Spanish Association of Surgeons (AEC), that included 31 questions regarding postoperative VTE and its prevention, as well as three clinical scenarios.

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Article Synopsis
  • Cholangiocarcinoma is a serious liver cancer with a low survival rate, and surgery is currently the only treatment option that can cure it.
  • Liver transplantation (LT) is recognized as the best treatment for another type of liver cancer, hepatocellular carcinoma, but there's potential for LT to help patients with intrahepatic cholangiocarcinoma (iCC).
  • Research from a center revealed a case of successful incidental LT in an iCC patient with a 10-year survival, suggesting that updates to LT criteria could improve treatment options as donor availability increases.
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Liver grafts from donors after cardiac death (DCD) involve a risk of failure owing to warm ischemia, among other factors. To minimize this important issue, new systems like normothermic regional perfusion have arisen. We report an observational and unicentric study focused on the results of liver transplantation after DCD, performing normothermic regional perfusion using extracorporeal membrane oxygenation.

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Purpose: Knowledge about compliance with recommendations derived from the positional statement of the European Society of Endocrine Surgeons on modern techniques in primary hyperparathyroidism surgery and the Third International Workshop on management of asymptomatic primary hyperparathyroidism is scarce. Our purpose was to check it on a bi-national basis and determine whether management differences may have impact on surgical outcomes.

Methods: An online survey including questions about indications, preoperative workup, surgical approach, intraoperative adjuncts, and outcomes was sent to institutions affiliated to the endocrine surgery divisions of the National Surgical Societies from Spain and Portugal.

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Background: Thyroidectomy is considered to be a safe procedure. Although very uncommon, death may occur after thyroid resection. The aim of this study was to investigate the prevalence and causes of death after thyroidectomy and the associated risk factors in the modern era of thyroid surgery.

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Clinical pathways are care plans applicable to patient care procedures that present variations in practice and a predictable clinical course. They are designed not as a substitute for clinical judgment, but rather as a means to improve the effectiveness and efficiency of the procedures. This clinical pathway is the result of a collaborative work of the Sections of Endocrine Surgery and Quality Management of the Spanish Association of Surgeons.

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Background: Parathyroid carcinoma (PC) is an uncommon disease that generally is detected postoperatively and traditionally is associated with a poor prognosis. Our purpose was to evaluate treatment outcomes, prognostic factors, and usefulness of some proposed staging systems for this disease.

Methods: A multicenter review of patients with surgically resected PC was performed, led by the Spanish Association of Surgery.

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Background: We assessed the results of adrenalectomy for solid tumor metastases in 317 patients recruited from 30 European centers.

Methods: Patients with histologically proven adrenal metastatic disease and undergoing complete removal(s) of the affected gland(s) were eligible.

Results: Non-small cell lung cancer (NSCLC) was the most frequent tumor type followed by colorectal and renal cell carcinoma.

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