Breast-conserving surgery in breast cancer and intraoperative radiotherapy. Can we predict the fibrosis?

Introduction: Radiotherapy techniques associated with breast-conserving surgery have evolved in early breast cancer thanks to a better knowledge of tumor radiobiology, highlighting intraoperative radiotherapy (IORT). However, complications have been documented with this procedure, mainly fibrosis. Transforming growth factor beta (TGF-β) is a cytokine with an active role in radiation-induced fibrosis, which could be used as an early biomarker for the development of fibrosis.

Abdominal injuries treated in a referral hospital: analysis of outcomes, treatment approaches, and prognostic scales.

Objectives: To describe the abdominal injuries treated in our hospital. We assessed the behavior and reliability of prognostic scales, analyzing the correlations between them and therapeutic decisions and outcomes.

Material And Methods: Retrospective study including all patients with major abdominal injuries admitted to our hospital between 2009 and 2015.