Idiopathic orbital inflammation with intracranial extension. Case report.

Idiopathic orbital inflammation or orbital pseudotumor with intracranial extension is a rare condition. It consists of a nonspecific infiltrate of the fatty tissue of the orbit that extends through one or more foramina into the adjacent intracranial tissue. The lesion mimics an infectious or neoplastic lesion.

Diagnosis and treatment of extreme lateral lumbar disc herniation.

Extreme lateral lumbar disc herniation is located in the foramen and compresses the exiting root producing symptoms attributed to the upper nerve root of the involved disc and vertebral level. The diagnosis is best established by using magnetic resonance imaging which visualizes the foramen in an axial and sagittal plane. Surgical treatment may be varied, but a posterior midline approach with drilling of the pars interarticularis will easily expose the nerve root and the herniated disc in the foramen.

Petrous apex region. Surgical anatomy, lesions, and operative techniques.

The author describes the anatomy of the region of the petrous apex giving emphasis to the limits of surgical resection. The cochlea, located at the apex of the angle formed by the intersection of a line along the sphenopetrosal groove and a line from the facial hiatus to the internal auditory canal, has to be protected to preserve hearing. Surgical approaches can be divided in the posterior presigmoid approach that provides exposure to the posterior petrous bone and upper two thirds of the clivus, and the anterior subtemporal approach that provides exposure to the trigeminal ganglion, petrous carotid artery, Meckel's cave, and posterior cavernous sinus.

Cystic meningiomas: a review.

Cystic meningiomas are uncommon tumors that are easily confused with metastatic or glial tumors that have cystic components. We have retrospectively reviewed all of the meningiomas operated on at the University of Puerto Rico in a 5-year period (1989-1993) and found only five cystic meningiomas (4.3% of total meningiomas).

Thoracic spine osteochondroma causing spinal cord compression. An unusual cause of paraparesis.

A case of a thoracic osteochondroma with compression of the spinal cord is reported. The neuroimaging studies are described.

Pleomorphic xanthoastrocytoma with invasion of the tentorium and falx.

A case of a 21-year-old patient with a recurrent pleomorphic xanthoastrocytoma with invasion of the tentorium and falx cerebri is reported. Dural attachment has been reported in some cases. Invasion of the dura of the falx cerebri and complete infiltration of the left tentorium by the tumor were found intraoperatively.

Sudden appearance of multiple brain lesions in Aids after a cerebral biopsy. Case report.

A unique case of cerebral toxoplasmosis which had an acute appearance of multiple discrete lesions following a biopsy and its neuroradiological findings are reported in detail. Possible pathophysiological mechanism are presented.

Radiobrominated m-tyrosine analog as potential CNS L-dopa pet tracer.

Radiobrominated 6-bromo-m-tyrosine (6-BMT) was prepared and the time course of its localization in selected cerebral and peripheral organs in the mouse was determined. Since m-tyrosine is known to have L-dopa-like properties in vivo, our goal was to assess the utility of a radiolabeled analog as a tracer for cerebral L-dopa. Our preliminary results showed that substantial amounts of 6-BMT is extracted by the mouse brain and that the regional distribution and time course of the radiotracer is consistent with uptake in regions rich in dopamine neurons.

Production of 75Br via the 78Kr (d,n alpha)75Br reaction.

The production of 75Br by the 78Kr (d,n alpha)75Br reaction using a 21.5 MeV deuteron beam was investigated. With our 78Kr gas target, the production yield was found to be 5.

Exogenous l-dopa alters spiroperidol binding, in vivo, in the mouse striatum.

The effect of exogenous l-dopa on the binding of tritiated spiroperidol, in vivo, in the murine striatum was investigated. The results obtained demonstrated that the binding of 3H-spiroperidol can be altered by the administration of l-dopa. This effect appears to be related to both the dose of spiroperidol and l-dopa given.

Radiobrominated spiroperidol for the study of dopamine D2 receptors.

Some neuropsychiatric disorders have been suggested to be related to the CNS dopaminergic system. In order to probe this neurotransmitter system, radiobrominated spiroperidol, a potent dopamine (DA) D2-receptor antagonist, was developed. This review deals with the routine synthesis of [75, 76, or 77Br]-p-bromospiroperidol (BrSP), its validation as a radiopharmaceutical directed to DA D2 receptors, and the imaging studies which have been done using this radioligand with either single photon tomography (SPECT) or positron tomography (PET).