Profile of Brazilian inpatients with COVID-19 vaccine breakthrough infection and risk factors for unfavorable outcome.

Objective: To characterize the epidemiological and clinical profile of individuals more likely to become infected with SARS-CoV-2 after the fully vaccination schedule in order to profile priority groups to receive a booster dose in situations of vaccine doses shortage as well as for maintenance of personal protective care.

Methods: This cross-sectional study used data from hospitalized COVID-19 patients aged ≥18 years, who had been fully vaccinated and had a SARS-CoV-2 infection positive diagnosis collected from the SIVEP-Gripe database (Influenza Epidemiological Surveillance Information System) from January 18, 2021 to September 15, 2021. Demographic data, clinical symptoms and preexisting medical conditions (comorbidities) were analyzed.

Future teachers facing the use of technology for inclusion: A view from the digital competence.

Technologies provide a differential value to the training process, allowing for the generation of new environments, methodologies and resources that make it possible to attend to students in a more appropriate way. This potential is especially relevant in matters of inclusion, where technology is sometimes an indispensable element for learning. In this paper we explore the main advantages of the use of technology for the attention to diversity, taking into consideration the level of digital competence of future teachers and their perceptions regarding its use for the implementation of inclusive strategies.

Eco-innovation assessment of biodigesters technology: an application in cassava processing industries in the south of Brazil, Parana state.

Eco-innovations are innovations capable of helping to reduce the environmental impacts of production processes. In this sense, the adoption of models that assess comprehensively, in an integrated manner and in different perspectives, the general performance of these innovations allows managers to guide their decisions. The object of this research is the use of an eco-innovation in the production processes of cassava, where the waste generated is treated by biodigesters.

Arthroscopic Repair of Acetabular Cartilage Lesions by Chitosan-Based Scaffold: Clinical Evaluation at Minimum 2 Years Follow-up.

Purpose: To evaluate the functional outcome of using chitosan-based material in our patients after 2 years of follow-up.

Methods: Nonarthritic nondysplastic femoroacetabular impingement patients with an acetabular chondral lesion, 18 to 55 years of age, were included for arthroscopic repair between May 2013 and July 2015. Full-thickness chondral defects ≥2 cm were filled with chitosan-based implant after microfractures.

Results of arthroscopic treatment of chondral delamination in femoroacetabular impingement with bone marrow stimulation and BST-CarGel.

Objectives: The purpose of this study is to show the preliminary results of using chitosan-based scaffold (BST-CarGel) with microfracture for treatment of acetabular chondral delamination associated with femoroacetabular impingement.

Methods: A prospective study was performed on 13 hips. Patients were selected in the age group between 18 and 50 years.

Is diffusion tensor imaging useful in the assessment of the sciatic nerve and its pathologies? Our clinical experience.

Objective: To evaluate the usefulness of diffusion tensor imaging (DTI) in the clinical setting as a complementary tool to conventional MRI in the study and assessment of the sciatic nerve and its pathologies.

Methods: 17 patients diagnosed with different types of sciatic neuropathy and 10 healthy controls underwent a conventional MRI and a DTI study in a 3-T MR scanner (Achieva(®) 3-T X-Series; Philips Healthcare, Netherlands).

Results: In the control group, we were able to track and visualize the common sciatic nerve and its main branches from hip to foot.

Arthroscopic Treatment of Hip Chondral Defects With Bone Marrow Stimulation and BST-CarGel.

Microfracture, the current standard of care for the treatment of non-degenerative chondral lesions in the hip joint, is limited by the poor quality of the filling fibrocartilaginous tissue. BST-CarGel (Piramal Life Sciences, Laval, Quebec, Canada) is a chitosan-based biopolymer that, when mixed with fresh, autologous whole blood and placed over the previously microfractured area, stabilizes the blood clot and enhances marrow-triggered wound-healing repair processes. BST-CarGel has been previously applied in the knee, with statistically significant greater lesion filling and superior repair tissue quality compared with microfracture treatment alone.

Religious beliefs or physicians' behavior: what makes a patient more prone to accept a physician to address his/her spiritual issues?

The present study aims to understand the relation between religious beliefs, physicians' behavior and patients' opinions regarding "Spirituality, religiosity and health (S/R)" issues, and what makes a patient more prone to accept a physician to address his/her spiritual issues. A cross-sectional study was carried out in outpatients from a tertiary hospital, and a path analysis was used to examine the direct and indirect relationships between the variables. For the final analysis, 300 outpatients were evaluated.

A novel system for organ and tissues preservation: the refrigerating hyperbaric chamber.

Unlabelled: This study was designed to investigate the feasibility of building a simple and inexpensive device to preserve organs or tissues in hyperbaric and hypothermic conditions.

Methods: The device was built on a 40-cm wide, 28-cm long, and 23-cm deep stainless steel chassis. The pressure vessel was built by a 7.

Apoptosis and nuclear proliferation in rat small bowel submitted to hypothermic hyperbaric oxygenation for preservation.

Unlabelled: This study was conducted to assess apoptosis and nuclear proliferation in rat small bowel submitted to hypothermic hyperbaric oxygenation for preservation.

Methods: Twenty two-month-old, male Wistar rats, weighing 250 g were divided into two groups: group I (n = 10), in which the small bowel was preserved for 12 hours, and group II (n = 10) in which the small bowel was preserved for 24 hours. After vascular and intraluminal perfusion, 3-cm segments were maintained in Ringer's solution at 2 degrees to 4 degrees C under normobaric conditions (groups Ia and IIa) or conditioned in a small hyperbaric metal chamber with 100% oxygen at 5.

Use of hyperbaric oxygenation in small bowel preservation for transplant.

Introduction: The aim of this work was to study the effects of hyperbaric oxygenation as a preservation technique for small bowel transplantation.

Methods: Twenty 2-month-old male Wistar rats weighting 250 g were divided into two groups: group A (n = 10) in which the small bowel was preserved for 12 hours, and group B (n = 10) in which the small bowel was preserved for 24 hours. After vascular and intraluminal perfusion, 3-cm segments were maintained in Ringer's solution at temperatures between 2 degrees C to 4 degrees C and in normobaric O2 conditions (groups A1, B1) or conditioned in an hyperbaric O2 metal chamber (100% oxygen at 5.

Rate limiting factors in melanocortin 1 receptor signalling through the cAMP pathway.

The melanotropic actions of alpha-melanocyte-stimulating hormone (alpha-MSH) and other melanocortins are mediated by activation of the melanocortin 1 receptor (MC1R). This G protein-coupled receptor is positively coupled to Gs and triggers the cyclic adenosine mono-phosphate (cAMP) pathway. Mutations of the MC1R gene are associated with skin type and pigmentation phenotypes, and with increased risk of skin cancers.