Restoration of endocrine function and fertility with orthotopic tubal-ovarian allotransplant as the anatomical-functional unit in rabbits.

The aim of this study was to re-establish endocrine and reproductive function in tubal-ovariectomized rabbits using orthotopic tubal-ovary allotransplants (OT-OA). Fifty-five New Zealand White nonconsanguineous rabbits were used and allocated into five experimental groups: Each group comprised donors submitted to right salpingo-oophorectomy that served as the donated allograft. In group 1 no cyclosporin (CsA) was administered and rabbits were submitted to left salpingo-oophorectomy (LSO).