Prenatal aneuploidy screening in a low-risk Hispanic population: price elasticity and cost-effectiveness.

Background: In October 2015, the Massachusetts Medicaid program temporarily stopped reimbursement for procedures in which the International Classification of Diseases, Tenth Edition, code for serum aneuploidy screening used by certain communities was stipulated. This change led to a substantial number of patients who went without aneuploidy screening for approximately 3 years.

Objective: This study aimed to determine the change in use and cost-effectiveness of prenatal aneuploidy serum screening in a low-risk Hispanic Medicaid population in Massachusetts.

Ag -Mediated Electrocatalytic Ambient CH Functionalization Inspired by HSAB Theory.

Although most class (b) transition metals have been studied in regard to CH activation, divalent silver (Ag ), possibly owing to its reactive nature, is the only class (b) high-valent transition metal center that is not yet reported to exhibit reactivities towards CH activation. We now report that electrochemically generated Ag metalloradical readily functionalizes CH into methyl bisulfate (CH OSO H) at ambient conditions in 98 % H SO . Mechanistic investigation experimentally unveils a low activation energy of 13.

Ambient methane functionalization initiated by electrochemical oxidation of a vanadium (V)-oxo dimer.

The abundant yet widely distributed methane resources require efficient conversion of methane into liquid chemicals, whereas an ambient selective process with minimal infrastructure support remains to be demonstrated. Here we report selective electrochemical oxidation of CH to methyl bisulfate (CHOSOH) at ambient pressure and room temperature with a molecular catalyst of vanadium (V)-oxo dimer. This water-tolerant, earth-abundant catalyst possesses a low activation energy (10.