Publications by authors named "Jesudasan C"
Purpose: To describe the influence of corrected refractive error on measured torsional fusional amplitudes (TA) by comparing the TA between emmetropes and spectacle corrected myopes, using the after-image slides of the synoptophore, as targets.
Methods: Fifty emmetropes (Group I) and 50 myopes (Group II) with best-corrected acuity of 6/6 in each eye were included in the study. Near point of convergence (NPC), near point of accommodation (NPA), and horizontal fusional amplitudes (HFA) were assessed in all the subjects.
We report a case of keratitis due to Fusarium langsethiae in a 56-year-old man. The patient presented with pain and tearing of 10 days duration in the right eye, which had sustained a paddy stalk injury. On examination, a hypopyon corneal ulcer was noted in the right eye.
View Article and Find Full Text PDFPurpose: The purpose of this study is to describe a case series of keratoconjunctivitis caused by a retained bindi (dot) in six children who presented to a tertiary eye care facility in Southern India.
Patients And Methods: Over a period of 11 years (January 2000 and January 2012), six children (all female, ranging in age from 6 months to 3 years) were diagnosed with ocular manifestations subsequent to a retained bindi.
Results: All patients presented with redness, photophobia, extensive lacrimation, and blepharospasm.
Background: In microspherophakia, abnormal laxity of the lenticular zonules leads to development of a spherical lens and possible subluxation. We evaluated long-term results of lens removal with scleral-fixated intraocular lens (SFIOL) implantation in microspherophakia.
Materials And Methods: Case series.
Putative free radical-scavenging activity of an extract of Cineraria maritima in preventing selenite-induced cataractogenesis in Wistar rat pups.
Mol Vis
July 2014
Purpose: To investigate the possible free radical-scavenging activity of an extract of Cineraria maritima on selenite-induced cataractous lenses in Wistar rat pups.
Methods: In the present study, Wistar rat pups were divided into three experimental groups. On P10, Group I (control) rat pups received an intraperitoneal injection of 0.
Keratitis due to Auerswaldia lignicola in a 32-year-old Indian male carpenter is described. At presentation, the patient reported persistent pain and tearing (left eye) in spite of topical antimicrobial therapy for more than 3 weeks. Clinically, mycotic keratitis was suspected, and direct microscopy of corneal scrapings stained by lactophenol cotton blue and Gram stains revealed broad septate hyphae.
View Article and Find Full Text PDFPurpose: To document transcriptional activation (expression) of key aflatoxin biosynthetic pathway genes in corneal isolates of Aspergillus flavus.
Methods: The expression of certain regulatory (aflatoxin regulatory [aflR] and aflatoxin J [aflJ]) and structural (polyketide synthase acetate [pksA] and norsolonic acid-1 [nor-1]) genes in four corneal A. flavus isolates was evaluated by reverse transcription PCR.
A 36-year-old man presented with a large tracheal carcinoid just above the carina. The size and location precluded surgical treatment and so he underwent bronchoscopic tumor resection using electrocautery. After approximately 80% of tumor removal, brisk hemorrhage from the tumor stalk necessitated endotracheal intubation with anatomic lung separation and use of high cuff pressure to tamponade the bleeding site.
View Article and Find Full Text PDFPurpose: To study the clinical and visual outcome and corneal topography in eyes that underwent full-thickness or lamellar eccentric-"shaped" (biconvex/crescentic) corneal grafts.
Setting: Tertiary care center in south India.
Methods: In this retrospective, interventional, noncomparative case series, eccentric-shaped corneal grafts were performed in 10 eyes (10 patients).
Purpose: To evaluate the efficacy of Pleurotus ostreatus extract in preventing selenite-induced cataractogenesis.
Methods: In vitro, enucleated rat lenses, divided into one control and three experimental groups (selenite only, simultaneous selenite and extract, initial extract and subsequent selenite), underwent morphological and biochemical evaluation. The anti-cataractogenic effect was also evaluated in vivo.
Purpose: To determine whether chlorazol black E, a chitin-specific stain, can be used to detect fungal filaments in corneal scrapings and to compare its sensitivity as a diagnostic aid for fungal keratitis with that of gram and lactophenol cotton blue stains.
Design: Prospective study, laboratory investigation.
Methods: Between December 1, 2005 and July 31, 2006, corneal scrapes from 163 patients with ulcerative keratitis were used for culture and to prepare smears that were stained by lactophenol cotton blue, chlorazol black E, or gram stains.
The present study sought to evaluate the efficacy of the naturally-occurring polyphenol, ellagic acid, in preventing selenite-induced cataractogenesis. In the present study, Wistar rat pups were divided into 3 groups of 15 each. Group I (normal) rats received an intraperitoneal (i.
View Article and Find Full Text PDFPurpose: To investigate whether acetyl-L-carnitine (ALCAR) retards selenite-induced cataractogenesis in vivo.
Methods: On postpartum day 10, group I pups received intraperitoneal saline and group II and group III pups received subcutaneous sodium selenite; Group III pups also received intraperitoneal ALCAR once daily on postpartum days 9-14. Both eyes of each pup were examined up to postpartum day 30.
Purpose: To report the clinical presentation, management and outcome of eyes with traumatic intralenticular abscess.
Methods: In this interventional case series, records of eight patients (eight eyes) with intralenticular abscess developing following trauma were reviewed. All patients underwent extracapsular cataract extraction with intracameral antibiotics with or without pars plana vitrectomy.
Bilateral keratitis usually occurs in predisposed individuals such as contact lens wearers, those suffering from malnutrition and immunodeficiency or patients undergoing bilateral refractive corneal surgery. We report a 30-year-old man without any obvious predisposing factors who presented with complaints of pain and decreased vision in both eyes. Examination revealed corneal ulcers in both eyes, which on microbiological culture grew Pseudomonas aeruginosa.
View Article and Find Full Text PDFPurpose: To report the optical coherence tomographic (OCT) features in eyes with tuberculous choroidal granuloma.
Design: Interventional case series.
Methods: Nine eyes of nine patients with tuberculous granuloma of the choroid were studied using OCT scans.
Purpose: To compare the per-operative contamination of anterior chamber among eyes undergoing manual small-incision cataract surgery (MSICS) and phacoemulsification (PE).
Design: Prospective, randomized, interventional clinical trial.
Methods: In this study conducted at a tertiary-care center in southern India, 150 eyes undergoing cataract surgery were randomly allocated to undergo MSICS (group A, 75 eyes) and PE (group B, 75 eyes).
Background: Ultrasonography is an important tool for evaluating the posterior segment in eyes with opaque media.
Aim: To study the incidence of posterior segment pathology in eyes with advanced cataract and to see whether certain features could be used as predictors for an abnormal posterior segment on ultrasound.
Setting: Tertiary care hospital in South India.
Purpose: To compare the bacteriologic and clinical efficacy of gatifloxacin and ciprofloxacin for the treatment of bacterial keratitis.
Design: Prospective, randomized clinical trial.
Methods: A total of 104 eyes of 104 patients with bacterial keratitis seen at a tertiary eye-care center were randomized to treatment with gatifloxacin 0.
Purpose: To study the risk factors, clinical presentation, response to treatment and outcome of microbial keratitis occurring in patients at extremes of age (ie, children and the elderly) and to compare them with microbial keratitis affecting the general adult population.
Methods: In this prospective, nonrandomized, analytical clinical study, all patients presenting with microbial keratitis and undergoing microbiological workup over a 1-year period were evaluated using a dedicated corneal ulcer protocol. Patients were divided into 3 groups based on age: (1) pediatric group if the age was 16 years or younger, (2) elderly group if the age was 65 years or older, and (3) control group if the age was between 17 and 64 years.
Purpose: To compare the clinical efficacy of itraconazole 1% eyedrops with a standard therapy regimen (natamycin 5% eyedrops) for topical monotherapy of fungal keratitis.
Methods: Patients presenting with suspected uniocular microbial keratitis over a period of 12 months (January to December 2002) underwent detailed clinical examination and microbiological investigation. One hundred consecutive patients with direct smear- and/or culture-proven fungal keratitis were enrolled in the study after obtaining informed consent.
Purpose: To assess the results of cataract surgery, in terms of visual outcome and effect on graft survival, in eyes that have previously undergone therapeutic penetrating keratoplasty for infective keratitis.
Methods: Case records of patients who had undergone cataract surgery alone (group A) or in combination with regrafting (group B) following initial therapeutic penetrating keratoplasty between January 2000 and December 2001 were reviewed retrospectively. Main outcome measures studied were visual acuity, astigmatism, and effect of the cataract surgery on graft survival.