Publications by authors named "Jessie Felton"
Article Synopsis
- There is a lack of strong evidence for effective treatments for juvenile localized scleroderma (JLS), with methotrexate (MTX) as the first-line choice and mycophenolate mofetil (MMF) as a second option, prompting the need for head-to-head trials to assess their relative benefits.
- An international expert meeting aimed to gather opinions on the efficacy and tolerability of MTX and MMF, which revealed that experts believe MMF may be superior in both areas, although there is still uncertainty among them.
- The study emphasizes the importance of utilizing a Bayesian approach for designing future clinical trials to integrate expert opinions and reduce pre-trial uncertainty, despite requiring a large sample size of 240
Epidermolysis bullosa (EB), notably severe recessive dystrophic EB (RDEB-S), is associated with increased risk of aggressive mucocutaneous squamous cell carcinomas, the major cause of mortality in early adulthood. This observational, retrospective case review describes a series of EB patients with cutaneous squamous cell carcinomas over a 28-year period. Forty-four EB patients with squamous cell carcinomas were identified with a total of 221 primary tumours.
View Article and Find Full Text PDFA case of multiple cerebral cavernomas associated with en coup de sabre scleroderma.
Pediatr Dermatol
January 2020
Linear scleroderma is a form of localized scleroderma that presents as band-like sclerotic lesions. When it occurs on the scalp or forehead, it is called "en coup de sabre scleroderma" (ECDS). Extracutaneous associations, mostly neurologic, have been described with ECDS.
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