Publications by authors named "Jessica de Andrade Gomes Silva"
Effects of Acylhydrazone Derivatives on Experimental Pulmonary Inflammation by Chemical Sensitization.
Katharina Rodrigues de Lima Porto Ramos Sandra Cabral da Silva Pascal Marchand Fernanda Virgínia Barreto Mota Julyanne Cunha de Assis Correia Jéssica de Andrade Gomes Silva Willian Charles da Silva Moura Teresinha Gonçalves da Silva
Antiinflamm Antiallergy Agents Med Chem
October 2022
Background: Chronic lung diseases are characterized by airway inflammation and remodelling of the lung parenchyma that triggers considerable impairment of respiratory function.
Objective: In this study, two compounds belonging to the N-acylhydrazone class were evaluated, aiming to identify new therapeutic agents for pulmonary inflammatory diseases.
Materials And Methods: The acute toxicity of 2-cyano-N'-(3-ethoxy-4-hydroxybenzylidene)- acetohydrazide (JR-12) and N'-benzylidene-2-cyano-3-phenylacrylohydrazide (JR09-Bz) was evaluated.