Publications by authors named "Jessica Vasiliou"
Patients' and health professionals' research priorities for chronic pain associated with inflammatory bowel disease: a co-produced sequential mixed methods Delphi consensus study.
BMJ Open Gastroenterol
September 2024
Article Synopsis
- People with inflammatory bowel disease (IBD) often have chronic pain that affects their daily lives.
- A survey was done with patients and doctors to find out the best treatment options, and they found that diets, especially the Low FODMAP diet, are really important.
- The results showed that both patients and healthcare professionals agree on the need for more research on diet and mental health therapies to help improve quality of life for those with IBD.
Background: Crohn's disease is a remitting and relapsing disorder that can affect the whole gastrointestinal tract. Active disease symptoms include abdominal pain, fatigue, weight loss, and diarrhoea. There is no known cure; however, the disease can be managed, and therefore places a huge financial burden on healthcare systems.
View Article and Find Full Text PDFAirway hyperresponsiveness (AHR) is a critical feature of wheezing and asthma in children, but the initiating immune mechanisms remain unconfirmed. We demonstrate that both recombinant interleukin-33 (rIL-33) and allergen [house dust mite (HDM) or ] exposure from day 3 of life resulted in significantly increased pulmonary IL-13CD4 T cells, which were indispensable for the development of AHR. In contrast, adult mice had a predominance of pulmonary LinCD45CD90IL-13 type 2 innate lymphoid cells (ILC2s) after administration of rIL-33.
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