The pyriform appendage, an organ only found in nautiloid cephalopods was investigated with histological, histochemical and ultrastructural methods in order to characterize the anatomical and the cytological structure of this organ. The pyriform appendage is situated within the genital septum and lies in close contact with the ventricle of the heart. The proximal side ends blindly near the gonad whereas the distal side is developed into a duct.
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