() is an increasingly common multidrug-resistant organism (MDRO) and is not part of the normal human flora. It is most commonly found in patients who are immunocompromised and/or in poor health, with multiple comorbidities. As an increasingly identified MDRO, needs to be identified early, especially in patients with multiple comorbidities, organ transplants, or on mechanical ventilation.
View Article and Find Full Text PDFPopular culture has long used skin conditions to suggest a character's immorality, deviancy, or to give the reader terror. This is especially obvious in Gothic literature, which utilizes dark themes including supernaturalism. Some examples of famous characters from Gothic literature include Frankenstein's monster creation that has jaundiced skin, Dracula who has albinism, poliosis, and an obvious scar, and finally, Stanton in Melmoth the Wanderer, who has albinism.
View Article and Find Full Text PDFLam Qua, a Chinese artist who painted in the Western style, was hired by American ophthalmologist and missionary Peter Parker to paint Parker's Chinese patients. Most of Lam Qua's paintings depict patients with rather large tumors located in various areas across the body; there are a few that are also of dermatologic interest. This contribution explores Lam Qua's paintings that depict a cutaneous horn, gangrenous necrosis, and an ulcerating tumor.
View Article and Find Full Text PDFis a mixed-media digital illustration that explores the importance of clinicians' word choices during their encounters with patients. Clinicians often face ethical questions about sharing information with vulnerable patients, dimensions of which are represented by the illustration's content and colors.
View Article and Find Full Text PDFThere is competing evidence that plasmacytoid dendritic cells (pDC), the most potent source of IFN-I, may initiate psoriasis. We targeted pDC function using the slc15a4 loss-of-function mouse whose pDC are unresponsive to TLR agonists. slc15a4 treated with the topical TLR7-agonist imiquimod (IMQ) demonstrated decreased epidermal thickening 24 hours post-treatment which was more pronounced by day 5 as compared to wildtype mice.
View Article and Find Full Text PDFAlopecia areata (AA) is a clinically heterogeneous disease that is characterized by nonscarring hair loss, nail changes, and increased risk of other autoimmune disease. During clinical visits, children with AA often report bullying. We report survey results that highlight the prevalence of bullying and surrounding emotional impact of AA in pediatric patients.
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