Publications by authors named "Jessica McKelvey"

Amyloid A (AA) amyloidosis is found in humans and non-human primates, but quantifying disease risk prior to clinical symptoms is challenging. We applied machine learning to identify the best predictors of amyloidosis in rhesus macaques from available clinical and pathology records. To explore potential biomarkers, we also assessed whether changes in circulating serum amyloid A (SAA) or lipoprotein profiles accompany the disease.

View Article and Find Full Text PDF
Article Synopsis
  • This study explores the genetic factors contributing to obesity in rhesus macaques, noting a lack of similar research in this species despite previous metabolic studies.
  • Researchers examined various physical traits related to adiposity in 583 macaques and found moderate heritability rates for these traits, with stronger heritability in females compared to males.
  • Genetic analysis revealed significant correlations among obesity-related traits and identified several mutations in human obesity genes, suggesting a polygenic influence on weight gain in macaques.
View Article and Find Full Text PDF

Infection with porcine epidemic diarrhea virus (PEDV) causes diarrhea, vomiting, and high mortality in suckling pigs. Contaminated feed has been suggested as a vehicle of transmission for PEDV. The objective of this study was to compare thermal and electron beam processing, and the inclusion of feed additives on the inactivation of PEDV in feed.

View Article and Find Full Text PDF

Salmonella enterica serovar Enteritidis (S. Enteritidis) is a major etiologic agent of nontyphoid salmonellosis in the United States. S.

View Article and Find Full Text PDF

The northern bobwhite (Colinus virginianus) is an ecologically and economically important avian species. At the present time, little is known about the microbial communities associated with these birds. As the first step to create a quail microbiology knowledge base, the current study conducted an inventory of cultivable quail tracheal, crop, cecal, and cloacal microbiota and associated antimicrobial resistance using a combined bacteriology and DNA sequencing approach.

View Article and Find Full Text PDF