Using pyrene to probe the effects of poloxamer stabilisers on internal lipid microenvironments in solid lipid nanoparticles.

Solid lipid nanoparticles (SLNs) have proved to be effective nanocarriers with many advantages over other non-lipid-based systems. The development of new SLN formulations is often hindered through poor drug loading capacity and time-consuming optimisation of lipid/stabiliser combinations. One challenge in the development of new SLN formulations is understanding the complex interactions between amphiphilic stabilisers and hydrophobic lipids; the nature of these interactions can significantly impact SLN properties, including the internal polarity within the nanoparticle core.

Relationship of Christian Beliefs to Attitudes Toward People With Mental Illness.

This study assessed the influence of Christian beliefs on attitudes toward people with mental illness. Participants (N=204) provided demographic information and completed the Christian Orthodoxy Scale, the Religious Fundamentalism Scale, and the Attitudes to Mental Illness Questionnaire. Participants read vignettes of a person with a mental illness (schizophrenia), a general medical illness (diabetes), and a control condition (practicing Christian) and rated them on five criteria representing stigmatizing attitudes.