Hypoglycaemia incidence with a simple, low-dose insulin protocol for adult diabetic ketoacidosis.

Objective: The objective of this study is to validate the glycaemic safety of a simple insulin protocol using weight-based insulin rates adapted from American guidance for the management of adult diabetic ketoacidosis.

Methods: Measures of hypoglycaemia were retrospectively assessed in a single cohort of inpatient adults. The primary outcome was incidence of hypoglycaemia during insulin infusion.

Fixed-rate insulin for adult diabetic ketoacidosis is associated with more frequent hypoglycaemia than rate-reduction method: a retrospective cohort study.

Objective: To assess whether hypoglycaemia incidence during management of adult diabetic ketoacidosis (DKA) differed following transition from a fixed-rate insulin protocol to a protocol using an empiric insulin rate reduction after normoglycaemia.

Methods: We retrospectively reviewed charts from adult patients managed with a DKA order set before and after order set revision. In cohort 1 (n = 77), insulin rate was 0.

Spatial analysis of disparities in asthma treatment among adult asthmatics.

Background: Spatial analytic techniques can uncover important differences in asthma treatment and identify geographic areas with poor asthma management.

Objective: To review geographical differences in asthma treatment in an adult asthmatic population.

Methods: This was a retrospective, cross-sectional chart review study (n = 519) using Geographic Information System approaches to determine the impact of spatial access to pharmacies and other factors on inappropriate rescue and inadequate controller medication use.