Publications by authors named "Jessica Londono"
Introduction. Urinary sodium has been proposed as a prognostic marker and indicator of the diuretic response in patients with heart failure. However, study results are heterogeneous.
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- The study aimed to analyze how different components of Early Goal-Directed Therapy (EGDT) and antibiotic use affect patient outcomes, specifically length of stay and mortality in hospitals.
- In a cohort of 884 adult patients with infections and low blood pressure or high lactate levels, researchers found a hospital mortality rate of 17%, with antibiotics administered within the first 3 hours showing a significant 21% reduction in mortality.
- Results indicated that for patients with high lactate levels, not decreasing lactate by at least 10% within 6 hours was linked to increased mortality, highlighting the importance of early antibiotic treatment and lactate management in emergency settings.
Article Synopsis
- The study investigates the relationship between lactate levels and clinical parameters in patients with shock, finding that traditional clinical signs do not effectively correlate with lactate levels.
- Conducted with 1,320 adult patients, the research shows that the lactate value at admission is the only strong predictor of mortality, with other clinical variables lacking strong discriminatory power to detect high lactate (hyperlactatemia).
- Ultimately, the results indicate that despite efforts to identify alternative screening tools, lactate remains a crucial marker for assessing the prognosis of patients experiencing shock.
Objectives: To perform a complete immunological characterization of compensatory anti-inflammatory response syndrome in patients with sepsis and to explore the relationship between these changes and clinical outcomes of 28-day mortality and secondary infections.
Design: Prospective single-center study conducted between April 2011 and December 2012.
Setting: ICUs from Hospital Universitario San Vicente Fundación at Medellin, Colombia.
Article Synopsis
- The study investigates the link between serum lactate levels and 28-day mortality in patients with sepsis but no hypotension, as this relationship has not been thoroughly studied before.
- Researchers analyzed data from 961 patients across various hospitals in Colombia, adjusting for factors like age, sex, and severity of illness.
- The results showed a significant correlation between higher lactate levels and increased odds of death, indicating that lactate can be an important prognostic marker for mortality in these patients.