Activation Pathways of Murine Macrophages by Lipophosphoglycan from Strains of (FV1 and LV39).

Lipophosphoglycan (LPG) is an important virulence factor. It is the most abundant surface glycoconjugate in promastigotes, playing an important role in the interaction with phagocytic cells. While LPG is known to modulate the macrophage immune response during infection, the activation mechanisms triggered by this glycoconjugate have not been fully elucidated.