Critical power and work-prime account for variability in endurance training adaptations not captured by V̇o.

Responses to exercise at a given percentage of one's maximum rate of oxygen consumption (V̇o), or percentage of the power associated with V̇o during a graded exercise test (i.e., P), vary.

Localized Heat Therapy Improves Mitochondrial Respiratory Capacity but Not Fatty Acid Oxidation.

AIM: Mild heat stress can improve mitochondrial respiratory capacity in skeletal muscle. However, long-term heat interventions are scarce, and the effects of heat therapy need to be understood in the context of the adaptations which follow the more complex combination of stimuli from exercise training. The purpose of this work was to compare the effects of 6 weeks of localized heat therapy on human skeletal muscle mitochondria to single-leg interval training.