Ultrafast Detection of Arsenic Using Carbon-Fiber Microelectrodes and Fast-Scan Cyclic Voltammetry.

Arsenic contamination poses a significant public health risk worldwide, with chronic exposure leading to various health issues. Detecting and monitoring arsenic exposure accurately remains challenging, necessitating the development of sensitive detection methods. In this study, we introduce a novel approach using fast-scan cyclic voltammetry (FSCV) coupled with carbon-fiber microelectrodes (CFMs) for the electrochemical detection of As.

Gold Nanoparticle-Modified Carbon-Fiber Microelectrodes for the Electrochemical Detection of Cd via Fast-Scan Cyclic Voltammetry.

Neurotoxic heavy metals, such as Cd, pose a significant global health concern due to their increased environmental contamination and subsequent detrimental health hazards they pose to human beings. These metal ions can breach the blood-brain barrierblood-brain barrier, leading to severe and often irreversible damage to the central nervous system and other vital organs. Therefore, developing a highly sensitive, robust, and rapid in vivo detection method for these hazardous heavy metal ions is of the utmost importance for early detection, thus initiating timely therapeutics.

Simultaneous detection of neurotransmitters and Cu using double-bore carbon fiber microelectrodes fast-scan cyclic voltammetry.

There is a great demand to broaden our understanding of the multifactorial complex etiology of neurodegenerative diseases to aid the development of more efficient therapeutics and slow down the progression of neuronal cell death. The role of co-transmission and the effect of environmental factors on such diseases have yet to be explored adequately, mainly due to the lack of a proper analytical tool that can perform simultaneous multi-analyte detection in real time with excellent analytical parameters. In this study, we report a simple fabrication protocol of a double-bore carbon-fiber microelectrode (CFM) capable of performing rapid simultaneous detection of neurotransmitters and Cu fast-scan cyclic voltammetry (FSCV) in Tris buffer.

Electrodeposition of dopamine onto carbon fiber microelectrodes to enhance the detection of Cu via fast-scan cyclic voltammetry.

The etiology of neurodegenerative diseases is poorly understood; however, studies have shown that heavy metals, such as copper, play a critical role in neurotoxicity, thus, adversely affecting the development of these diseases. Because of the limitations associated with classical metal detection tools to obtain accurate speciation information of ultra-low concentrations of heavy metals in the brain, analysis is primarily performed in blood, urine, or postmortem tissues, limiting the translatability of acquired knowledge to living systems. Inadequate and less accurate data obtained with such techniques provide little or no information for developing efficient therapeutics that aid in slowing down the deterioration of brain cells.

Recent Advances in Electrochemical Tools for Virus Detection.

Virus detection at the point-of-care facility has become an alarming topic in the research community. The latest coronavirus pandemic has highlighted the limitations of current conventional virus detection methods. Compared to nonelectrochemical sensors, electrochemical sensors provide the ideal platform for rapid, cheap, fast, sensitive, and selective diagnosis of several viruses, particularly at point-of-care facilities.

Electrochemical detection of Cd(ii) ions in complex matrices with nanopipets.

Heavy metal contamination and its detrimental health effects are a growing concern globally. Several metal mitigation systems and regulatory approaches have been implemented to minimize the negative impacts on human health. However, none of these function at maximum efficiency, mainly due to the lack of accurate information about metal speciation.

The electronic nature of terminal oxo ligands in transition-metal complexes: ambiphilic reactivity of oxorhenium species.

The synthesis of the Lewis acid-base adducts of B(C6F5)3 and BF3 with [DAAmRe(O)(X)] DAAm = N,N-bis(2-arylaminoethyl)methylamine; aryl = C6F5 (X = Me, 1, COCH3, 2, Cl, 3) as well as their diamidopyridine (DAP) (DAP=(2,6-bis((mesitylamino)methyl)pyridine) analogues, [DAPRe(O)(X)] (X = Me, 4, Cl, 5, I, 6, and COCH3,7), are described. In these complexes the terminal oxo ligands act as nucleophiles. In addition we also show that stoichiometric reactions between 3 and triarylphosphine (PAr3) result in the formation of triarylphosphine oxide (OPAr3).

Mechanism for the activation of carbon monoxide via oxorhenium complexes.

Activation of CO by the rhenium(V) oxo complex [(DAAm)Re(O)(CH(3))] (1) [DAAm = N,N-bis(2-arylaminoethyl)methylamine; aryl = C(6)F(5), Mes] resulted in the isolation of the rhenium(III) acetate complex [(DAAm)Re(O(2)CCH(3))(CO)] (3). The mechanistic details of this reaction were explored experimentally. The novel oxorhenium(V) acyl intermediate [(DAAm)Re(O)(C(O)CH(3))] (2) was isolated, and its reactivity with CO was investigated.