Age-Related Changes to Multisensory Integration and Audiovisual Speech Perception.

Multisensory integration is essential for the quick and accurate perception of our environment, particularly in everyday tasks like speech perception. Research has highlighted the importance of investigating bottom-up and top-down contributions to multisensory integration and how these change as a function of ageing. Specifically, perceptual factors like the temporal binding window and cognitive factors like attention and inhibition appear to be fundamental in the integration of visual and auditory information-integration that may become less efficient as we age.

Age-related changes to the attentional modulation of temporal binding.

During multisensory integration, the time range within which visual and auditory information can be perceived as synchronous and bound together is known as the temporal binding window (TBW). With increasing age, the TBW becomes wider, such that older adults erroneously, and often dangerously, integrate sensory inputs that are asynchronous. Recent research suggests that attentional cues can narrow the width of the TBW in younger adults, sharpening temporal perception and increasing the accuracy of integration.

Comparison of real-time, quantitative PCR with molecular beacons to nested PCR and culture methods for detection of Mycobacterium avium subsp. paratuberculosis in bovine fecal samples.

An automated PCR with fluorescent probes (molecular beacons) detected Mycobacterium avium subsp. paratuberculosis in bovine feces. When the PCR was compared with culture in testing 41 fecal samples, kappa scores of 0.