Moderation Effects of Substance Use on Physical and Mental Well-Being in Adults.

Background: Each year about one in five adults experiences mental illness. Although the independent physical and mental health consequences of alcohol misuse and cigarette smoking are well documented, little is known on how substance use moderates the relationship between physical and mental well-being.

Aim: The purpose of this study was to examine whether substance use moderates the relationship between physical activity and mental health in adults.