Cannulation approach and mortality in neonatal ECMO.

Objective: Identify associations between cannulation approach and mortality in neonates who received ECMO support for respiratory failure.

Study Design: A retrospective analysis of neonates receiving ECMO for respiratory indications at a single quaternary-referral NICU. Associations between cannulation approach and mortality were assessed after adjustment for Neo-RESCUERS score.

Red blood cell volume, but not platelet or plasma volume is associated with mortality in neonatal ECMO.

Background: Blood product transfusions are necessary for critically ill neonates on extracorporeal membrane oxygenation (ECMO). Transfusions are administered in response to unstudied arbitrary thresholds and may be associated with adverse outcomes. The objective of this study was to identify relationships between blood product components and mortality in neonates receiving ECMO support for respiratory indications.