Publications by authors named "Jessica L Diaz"
An evolutionarily acquired microRNA shapes development of mammalian cortical projections.
Proc Natl Acad Sci U S A
November 2020
Article Synopsis
- The corticospinal tract and corpus callosum are specialized structures in mammals that contribute to advanced motor and cognitive abilities.
- Researchers have identified 17 specific microRNAs (miRNAs) that are enriched in corticospinal motor neurons, 15 of which originate from a unique genomic cluster found only in placental mammals.
- One particular miRNA, miR-409-3p, plays a crucial role in determining the identity of corticospinal motor neurons by inhibiting a gene involved in developing another type of neuron, showcasing how evolution has influenced neuronal diversity in mammals.
The circulatory system consists of veins and arteries. Compared with arteries, veins have been neglected in cardiovascular research. Although veins are significantly less muscular than similarly sized arteries, the contribution of veins to cardiovascular homeostasis cannot be left un-noted because veins accommodate 70% of the circulating blood.
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