Publications by authors named "Jessica Kuppan"
The complement system is a critical host defense against infection, playing a protective role that can also enhance disease if dysregulated. Although many consequences of complement activation during viral infection are well established, mechanisms that determine the extent to which viruses activate complement remain elusive. Here, we investigate complement activation by human respiratory syncytial virus (RSV), a filamentous respiratory pathogen that causes significant morbidity and mortality.
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- Researchers introduced a new method using ring-opening metathesis polymerization (ROMP) to control VLP disassembly without relying on specific environmental factors like pH and temperature.
- The study demonstrated that this ROMP strategy was effective for the P22 bacteriophage-derived VLP, allowing the release of a GFP reporter and showing potential for adapting this method for other VLPs in drug delivery applications.
DNA barcoding is both an important research and science education tool. The technique allows for quick and accurate species identification using only minimal amounts of tissue samples taken from any organism at any developmental phase. DNA barcoding has many practical applications including furthering the study of taxonomy and monitoring biodiversity.
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