Publications by authors named "Jessica J Anderson"
Cost-Benefit Analysis of a Pediatric ICU Sedation Weaning Protocol.
J Pediatr Pharmacol Ther
October 2024
Article Synopsis
- A retrospective study in a pediatric intensive care unit assessed the impact of a risk stratified sedation weaning protocol on medication costs and patient outcomes over a two-year period.
- The results showed that implementing the protocol reduced total sedation weaning costs significantly from approximately $400,329 to around $170,459, with lower median costs per patient.
- Despite the cost reduction, the incidence of withdrawal symptoms before and after the protocol remained similar, indicating that patient outcomes were not adversely affected by the change.
Article Synopsis
- This study investigated the effects of ketamine on intracranial pressure (ICP) and cerebral perfusion pressure (CPP) in children with severe traumatic brain injury (TBI).
- Using a retrospective analysis of 33 patients, the study found no increase in ICP after ketamine administration, which is significant as it suggests safety in using ketamine for sedation or during ICP crises.
- Ketamine was associated with a decrease in ICP and an increase in CPP during ICP crises, indicating its potential as a therapeutic option for managing TBI in children if confirmed in further research.