Publications by authors named "Jessica Folek"

Molecular testing (MT) is commonly used to refine cancer probability in thyroid nodules with indeterminate cytology. Whether or not ultrasound (US) patterns and clinical parameters can further inform the risk of thyroid cancer in nodules predicted to be positive or negative by MT remains unknown. The aim of this study was to test if clinical parameters, including patient age, sex, nodule size (by US), Bethesda category (III, IV, V), US pattern (American Thyroid Association [ATA] vs.

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Article Synopsis
  • About 20% of fine-needle aspirations (FNAs) of thyroid nodules yield indeterminate results, often classified under Bethesda categories III or IV, and diagnosing these nodules accurately can potentially reduce unnecessary surgeries.
  • A study was conducted involving 782 patients with 1013 thyroid nodules to assess the effectiveness of a multigene classifier test (ThyroSeq v3) in distinguishing benign from malignant nodules.
  • The results showed that the test had a high sensitivity of 94% and a specificity of 82%, with a negative predictive value of 97%, effectively identifying benign nodules and helping to prevent surgery in low-risk cases.
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Background: Measurement of intraoperative parathyroid hormone (PTH) levels is an important adjunct to confirm biochemical cure during parathyroidectomy. The purpose of this study was to evaluate a simplified anatomic technique for PTH sampling from the central veins through the minimally invasive neck incision, and to compare the predictive accuracy of central and peripheral PTH values.

Methods: A specific anatomic method for central PTH sampling was employed in 48 patients.

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Introduction: Minimally invasive adrenalectomy is commonly performed by either a transperitoneal laparoscopic (TLA) or posterior retroperitoneoscopic (PRA) approach. Our group described the technique for robot-assisted PRA (RAPRA) in 2010. Few studies are available that directly compare outcomes between the available operative approaches.

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