Antimicrobial Monotherapy versus Combination Therapy for the Treatment of Complicated Intra-Abdominal Infections.

Study Objective: It is unknown if β-lactam monotherapy is sufficient for complicated intra-abdominal infections or if broader coverage is required, such as with vancomycin. This study sought to determine the clinical outcomes of piperacillin/tazobactam (PIP/TAZ) monotherapy compared to combination therapy with vancomycin and PIP/TAZ for complicated intra-abdominal infections among patients within a surgical intensive care unit (ICU).

Design: Retrospective cohort study.

Antithymocyte Globulin Induction Therapy in Liver Transplant: Old Drug, New Uses.

Objective: To review the use of rabbit antithymocyte globulin (rATG) induction therapy in liver transplant recipients.

Data Sources: A MEDLINE literature search (inception to March 2016) was conducted using the search terms rabbit antithymocyte globulin, liver transplantation, and induction References from extracted sources were further searched for any relevant, missed data sources.

Study Selection And Data Extraction: All English-language randomized and observational studies were included.

Future prospects in immunosuppression for liver transplantation.

1. Our increasing understanding of signaling pathways and cellular interactions in transplant immunobiology and the availability of novel immunosuppressive agents have facilitated targeted strategies. 2.

Stability of diluted adenosine solutions in polyvinyl chloride infusion bags.

Purpose: The stability of diluted adenosine solutions in polyvinyl chloride infusion bags was studied.

Methods: Adenosine 50-, 100-, and 220-μg/mL solutions were prepared in 50-mL polyvinyl chloride (PVC) infusion bags containing 0.9% sodium chloride injection or 5% dextrose injection and stored at room temperature (23-25 °C) or under refrigeration (2-8 °C).