Conceptualizing race in research.

Background: The use of race as a variable in research continues to spark debate about whether it should be used, as well as the implications it has for research on health differences. Given this continued controversy, we examined how investigators interpret the concept of "race" and whether their views of race are reflected in their published work.

Methods: Thirty-three semistructured interviews were conducted with investigators from 3 southeastern universities to discuss recruitment of participants, the use of race as a variable in research and analyses, and their assessment of the National Institutes of Health mandate on the inclusion of women and minorities.

Studying genetic research participants: lessons from the "Learning About Research in North Carolina" study.

Given the prohibitive cost of recruiting large and diverse populations for genetic explorations in cancer research, there has been a call for genetic studies to engage existing cohorts of research participants. This strategy could lead to more efficient recruitment and potentially result in significant advances in the understanding of cancer etiology and treatment. The Learning About Research in North Carolina (LeARN) study responded to the National Human Genome Research Institute interest in research on how study participants from diverse populations who had participated in genetic research perceived the risks and benefits of participating in combined epidemiologic-genetic research, how well they understand the purpose of the research and the uses to which the research results may be put, and how involvement in such research affects perceptions of disease causality.

Relationships and communication in minority participation in research: multidimensional and multidirectional.

We examined the range and nature of investigators' communication and relationship building as they recruit minority participants in their research. Semistructured, in-depth interviews were conducted with 33 investigators conducting research with human participants. The response rate was 77%.