Publications by authors named "Jessica D'Angelo"

Article Synopsis
  • Long-acting injectable cabotegravir and rilpivirine have proven effective and safe for adults with HIV-1, making their use in adolescents a focus of the MOCHA study, which assessed acceptability and tolerability for participants aged 12-17.
  • The study involved 55 adolescents who had stable HIV-1 treatment, measuring pain levels from injections and overall quality of life through surveys and interviews over several weeks.
  • Results indicated high acceptability, with 83% of participants reporting minimal pain after the first injection and a significant number showing a positive response to the treatment by week 8.
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Satellite RNAs (satRNAs) are a class of small parasitic RNA replicon that associate with different viruses, including plus-strand RNA viruses. Because satRNAs do not encode a polymerase or capsid subunit, they rely on a companion virus to provide these proteins for their RNA replication and packaging. SatRNAs recruit these and other required factors via their RNA sequences and structures.

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