Effects of Selenium treatment on cardiac function in Chagas heart disease: Results from the STCC randomized Trial.

Background: Chagas disease (caused by infection) evolves to chronic chagasic cardiomyopathy (CCC) affecting 1.8 million people worldwide. This is the first randomized, placebo-controlled, double-blinded, clinical trial designed to estimate efficacy and safety of selenium (Se) treatment in CCC.