An optimised glucose oxidase bioelectrode exhibiting high performance direct electron transfer.

A glucose oxidase (GOd) bioelectrode exhibiting high performance, direct electron transfer (DET) has been prepared. Unprecedented redox peak current densities of 1 mA cm(-2) were observed alongside a clear electrochemical response to glucose. This system shows potential as a low cost, high performance enzymatic bioelectrode.

Multiple functionalization of single-walled carbon nanotubes by dip coating.

Single walled carbon nanotubes were functionalized with different functionalities by simple dip coating. This fast and reproducible procedure was realized with nanotube coated electrodes for the construction of polyvalent biosensors. Three different pyrene derivatives were attached to the nanotube sidewalls by π-stacking interactions in a one-step reaction.

Label-free femtomolar detection of target DNA by impedimetric DNA sensor based on poly(pyrrole-nitrilotriacetic acid) film.

An ultrahigh performance impedimetric DNA sensor is presented showing detection limits in the femtomolar range. This electrochemical setup was constructed initially by electrogeneration of poly(11-pyrrol-1-yl-undecanoic acid N(alpha'),N(alpha)-bis(carboxymethyl)-L-lysine amide) (poly(pyrrole-NTA)) film. The latter was then modified by the coordination of Cu(2+) ions onto the chelating NTA centers followed by the immobilization of the ssHIV-DNA previously modified by a polyhistidine tag by affinity binding.