The water extract and the lectin WSMoL from the seeds of Moringa oleifera prevent the hypertension onset by decreasing renal oxidative stress.

Maternal endotoxemia disturbs the intrauterine environment, impairs nephrogenesis, and increases the risk of hypertension and kidney disease in adulthood. Here, it was investigated whether maternal treatment with the water extract of Moringa oleifera seeds (WEMoS) or the water-soluble M. oleifera seed lectin (WSMoL) prevents the oxidative stress induced by lipopolysaccharide (LPS) in pregnant rats, and the renal injury and hypertension in the adult offspring.

Paricalcitol prevents renal tubular injury induced by ischemia-reperfusion: Role of oxidative stress, inflammation and ATR.

The vitamin D receptor (VDR) is associated with antioxidative and anti-inflammatory effects and modulation of the renin-angiotensin-aldosterone system. This study evaluated whether VDR agonist paricalcitol protects renal ischemia-reperfusion (IR) induced tubular injury in rats by evaluating: 1) ATP-dependent tubular Na transport; 2) renal redox signaling; 3) renal content of proinflammatory cytokines TNF-α and IL-6; and 4) renal content of renin and angiotensin II receptor type 1 (ATR). Paricalcitol prevented IR-induced tubular injury, evidenced by the prevention of histopathological changes and renal fibrosis with preservation of the activity of ATP-dependent Na transporters in the renal cortex.

Low-cost precision agriculture for sustainable farming using paper-based analytical devices.

The United Nations estimates that by 2030, agricultural production must increase by 70% to meet food demand. Precision agriculture (PA) optimizes production through efficient resource use, with soil fertility being crucial for nutrient supply. Traditional nutrient quantification methods are costly and time-consuming.

Perspectives of healthcare professionals on training for quantitative G6PD testing during implementation of tafenoquine in Brazil (QualiTRuST Study).

Effective radical cure of Plasmodium vivax malaria is essential for malaria elimination in Brazil. P. vivax radical cure requires administration of a schizonticide, such as chloroquine, plus an 8-aminoquinoline.

Anatomy and Diseases of the Greater Wings of the Sphenoid Bone.

The greater wings of the sphenoid bone (GWS) comprise the components of the sphenoid bone that make up most of the posterior orbital wall and form the anterior and medial parts of the floor of the middle cranial fossa. Many important skull base foramina, which transmit vital neurovascular structures, are present in these paired wings on either side of the central body of the sphenoid bone. A wide variety of diseases can affect the GWS, ranging from benign osseus lesions to malignant primary and secondary bone abnormalities.

Effects of transcranial direct current stimulation associated with an aerobic exercise bout on blood pressure and autonomic modulation of hypertensive patients: A pilot randomized clinical trial.

The objective of this article was to evaluate the effects of an aerobic exercise bout associated with a single session of anodal transcranial direct current stimulation (tDCS) over the left temporal lobe on blood pressure (BP) and heart rate variability (HRV) in hypertensive people. After met the inclusion criteria, twenty hypertensive people were randomized to active-tDCS or sham-tDCS group. Initially, they provided their sociodemographic data, a blood sample, and went through an evaluation of the cardiorespiratory performance.

Transcranial direct current stimulation as a strategy to manage COVID-19 pain and fatigue.

The novel coronavirus disease (COVID-19) has infected millions of people worldwide and generated many sequels in the survivors, such as muscular pain and fatigue. These symptoms have been treated through pharmacological approaches; however, infected people keep presenting physical limitations. Besides, the COVID-19 damage to the central nervous system has also been related to the presence of some physical impairment, so strategies that focus on diverse brain areas should be encouraged.

Comment on "The importance of physical exercise during the coronavirus (COVID-19) pandemic".

Currently, many people have been infected by the Coronavirus disease (COVID-19) and presented cardiorespiratory symptoms caused mainly by the host immune system response and respiratory tract inflammation. So far, there is no effective treatment to fight off COVID-19 and, despite many daily speculations about new treatments and vaccines, in this article, we discuss the effectiveness of a cheap and scientific proven technique to treat and prevent several diseases. Many studies have shown the benefits of physical exercise in individuals who have practiced it routinely.

Prevalence of musculoskeletal complaints and quality of life among administrative technicians.

Background: Work-related musculoskeletal disorders comprise muscle, tendon, synovial, nerve, fascial and ligament injuries alone or combined, with a proven or not relationship with work. They manifest as pain, paresthesia, feeling of heaviness and fatigue, and may cause temporary or permanent incapacity for work.

Objective: To establish the prevalence of musculoskeletal symptoms and quality of life of administrative technicians at a public institution who used computers at work for 5 years.

Health behaviors in sexual experiences of women in prison.

Objective: to describe the health behaviors related to the sexual experiences of women in the female prison system from January to March, 2017.

Method: descriptive study with a qualitative approach. A semi-structured questionnaire containing mixed questions and patient records was used.

Neuromodulation treats Chikungunya arthralgia: a randomized controlled trial.

The Chikungunya (CHIK) virus is epidemic in Brazil, with 170,000 cases in the first half of 2016. More than 60% of patients present relapsing and remitting chronic arthralgia with debilitating pain lasting years. There are no specific therapeutic agents to treat and rehabilitee infected persons with CHIK.