Publications by authors named "Jessica Alam"
Article Synopsis
- Premenopausal women have lower blood pressure and less hypertension compared to men, but this changes after menopause due to loss of estrogen.
- The review highlights physiological differences between sexes in kidney function, focusing on systems like renin-angiotensin and endothelin.
- Understanding these differences can help develop targeted treatments for hypertension and kidney diseases, taking into account sex and hormone levels.
Background: Glucocorticoids are the treatment of choice for proteinuric patients with minimal change disease (MCD) and primary focal segmental glomerulosclerosis (FSGS). Immunosuppressive as well as direct effects on podocytes are believed to mediate their actions. In this study, we analyzed the anti-proteinuric effects of inhibition of the glucocorticoid receptor (GR) in glomerular epithelial cells, including podocytes.
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