Publications by authors named "Jessica A S Pereira"
Article Synopsis
- Ghrelin, a hormone produced in the stomach, plays a key role in regulating immune responses, particularly through its effects on macrophages.
- The study shows that ghrelin can modify macrophage metabolism, leading to reduced secretion of inflammatory substances like TNF-α and IL-1β while increasing IL-12 production.
- Moreover, the research highlights that ghrelin’s effects depend on proper mitochondrial function, as impairments in mitochondrial processes can negate its beneficial impact on IL-12 secretion.
In the past decade, several reports have appointed the importance of mitochondria in the immune response. Our understanding of mitochondria evolved from a simple supplier of energy into a platform necessary for immunorregulation. Proinflammatory responses are associated with enhanced glycolytic activity and breakdown of the TCA cycle.
View Article and Find Full Text PDFGlycoside Hydrolases (GHs) are enzymes able to recognize and cleave glycosidic bonds. Insect GHs play decisive roles in digestion, in plant-herbivore, and host-pathogen interactions. GH activity is normally measured by the detection of a release from the substrate of products as sugars units, colored, or fluorescent groups.
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