Melphalan toxicity following treatment of retinoblastoma identified by pattern electroretinogram.

Purpose: To describe a patient with retinoblastoma and subsequent maculopathy unrelated to the tumor but related to intra-arterial melphalan documented by pattern electroretinography.

Methods: Comprehensive ophthalmic evaluation, treatment with intra-arterial chemotherapy and subsequent follow-up including electroretinography to assess for macular dysfunction.

Results: A 3-year-old child was evaluated with electrophysiological investigations following treatment of unilateral Group D retinoblastoma with intra-arterial and intravitreal chemotherapy with melphalan.

A comparison of the Grass strobe and new LED photic stimulator for paediatric electroretinogram recordings.

Purpose: This study evaluated a new light-emitting diode (LED-S) photic stimulator and compared skin electroretinogram (ERG) responses obtained to those evoked by the Grass Instrument stimulator (GP-S).

Methods: Two sub-studies were combined to evaluate the difference in responses resulting from the LED-S and GP-S stimuli. The first was a photometry study that matched the LED-S stimuli to the GP-S.

Developing a pediatric ophthalmology telemedicine program in the COVID-19 crisis.

Purpose: To describe our methodology for implementing synchronous telemedicine during the 2019 novel coronavirus (COVID-19) pandemic.

Methods: A retrospective review of outpatient records at a single children's hospital from March 21 to April 10, 2020, was carried out to determine the outcome of already-scheduled face-to-face outpatient appointments. The week leading up to the March 21, all appointments in the study period were categorized as follows: (1) requiring an in-person visit, (2) face-to-face visit that could be postponed, and (3) consultation required but could be virtual.