Informing policy via dynamic models: Cholera in Haiti.

Public health decisions must be made about when and how to implement interventions to control an infectious disease epidemic. These decisions should be informed by data on the epidemic as well as current understanding about the transmission dynamics. Such decisions can be posed as statistical questions about scientifically motivated dynamic models.

A Sub-millimeter, Inductively Powered Neural Stimulator.

Wireless neural stimulators are being developed to address problems associated with traditional lead-based implants. However, designing wireless stimulators on the sub-millimeter scale (<1 mm) is challenging. As device size shrinks, it becomes difficult to deliver sufficient wireless power to operate the device.

Human perception of electrical stimulation on the surface of somatosensory cortex.

Recent advancement in electrocorticography (ECoG)-based brain-computer interface technology has sparked a new interest in providing somatosensory feedback using ECoG electrodes, i.e., cortical surface electrodes.

Regenerated Sciatic Nerve Axons Stimulated through a Chronically Implanted Macro-Sieve Electrode.

Sieve electrodes provide a chronic interface for stimulating peripheral nerve axons. Yet, successful utilization requires robust axonal regeneration through the implanted electrode. The present study determined the effect of large transit zones in enhancing axonal regeneration and revealed an intimate neural interface with an implanted sieve electrode.

Package architecture and component design for an implanted neural stimulator with closed loop control.

An implanted neural stimulator with closed loop control requires electrodes for stimulation pulses and recording neuron activity. Our system features arrays of 64 electrodes. Each electrode can be addressed through a cross bar switch, to enable it to be used for stimulation or recording.

Risk of obesity at 4 to 6 years of age among overweight or obese 18-month-olds: community-based cohort study.

Objective: To determine whether high weight for length at the 18-month well-baby visit is predictive of overweight or obese body mass index (BMI) at the 4- to 6-year well-child visit.

Design: Retrospective cohort study using objective electronic medical record measurements.

Setting: Eighteen family practices forming a community family health organization in Peterborough, Ont.

Cortical adaptation to a chronic micro-electrocorticographic brain computer interface.

Brain-computer interface (BCI) technology decodes neural signals in real time to control external devices. In this study, chronic epidural micro-electrocorticographic recordings were performed over primary motor (M1) and dorsal premotor (PMd) cortex of three macaque monkeys. The differential gamma-band amplitude (75-105 Hz) from two arbitrarily chosen 300 μm electrodes (one located over each cortical area) was used for closed-loop control of a one-dimensional BCI device.