Automatic speech emotion recognition is a challenging task due to the gap between acoustic features and human emotions, which rely strongly on the discriminative acoustic features extracted for a given recognition task. We propose a novel deep neural architecture to extract the informative feature representations from the heterogeneous acoustic feature groups which may contain redundant and unrelated information leading to low emotion recognition performance in this work. After obtaining the informative features, a fusion network is trained to jointly learn the discriminative acoustic feature representation and a Support Vector Machine (SVM) is used as the final classifier for recognition task.
View Article and Find Full Text PDFAlzheimer's disease (AD) is characterized by an insidious onset of progressive cerebral atrophy and cognitive decline. Previous research suggests that cortical folding and sulcal width are associated with cognitive function in elderly individuals, and the aim of the present study was to investigate these morphological measures in patients with AD. The sample contained 161 participants, comprising 80 normal controls, 57 patients with very mild AD, and 24 patients with mild AD.
View Article and Find Full Text PDFWhile the conversion from mild cognitive impairment to Alzheimer's disease has received much recent attention, the transition from normal cognition to mild cognitive impairment is largely unexplored. The present pattern recognition study addressed this by using neuropsychological test scores and neuroimaging morphological measures to predict the later development of mild cognitive impairment in cognitively normal community-dwelling individuals aged 70-90years. A feature selection algorithm chose a subset of neuropsychological and FreeSurfer-derived morphometric features that optimally differentiated between individuals who developed mild cognitive impairment and individuals who remained cognitively normal.
View Article and Find Full Text PDFAmnestic mild cognitive impairment (aMCI) is a syndrome widely considered to be prodromal Alzheimer's disease. Accurate diagnosis of aMCI would enable earlier treatment, and could thus help minimize the prevalence of Alzheimer's disease. The aim of the present study was to evaluate a magnetic resonance imaging-based automated classification schema for identifying aMCI.
View Article and Find Full Text PDFPrediction of conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) is of major interest in AD research. A large number of potential predictors have been proposed, with most investigations tending to examine one or a set of related predictors. In this study, we simultaneously examined multiple features from different modalities of data, including structural magnetic resonance imaging (MRI) morphometry, cerebrospinal fluid (CSF) biomarkers and neuropsychological and functional measures (NMs), to explore an optimal set of predictors of conversion from MCI to AD in an Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort.
View Article and Find Full Text PDFThe relationship between cognitive functions and brain structure has been of long-standing research interest. Most previous research has attempted to relate cognition to volumes of specific brain structures or thickness of cortical regions, with relatively few studies examining other features such as cortical surface anatomy. In this study, we examine the relationship between cortical sulcal features and cognitive function in a sample (N=316) of community-dwelling subjects aged between 70 and 90 years (mean=78.
View Article and Find Full Text PDFA large number of structural brain studies using magnetic resonance imaging (MRI) have reported age-related cortical changes and sex difference in brain morphology. Most studies have focused on cortical thickness or density, with relatively few studies of cortical sulcal features, especially in the elderly. In this paper, we report global sulcal indices (g-SIs) of both cerebral hemispheres and the average sulcal span in six prominent sulci, as observed in T1-weighted scans obtained from a large community cohort of 319 non-demented individuals aged between 70 and 90 years (mean=78.
View Article and Find Full Text PDFSensor data fusion technology can be used to best extract useful information from multiple sensor observations. It has been widely applied in various applications such as target tracking, surveillance, robot navigation, signal and image processing. This paper introduces a novel data fusion approach in a multiple radiation sensor environment using Dempster-Shafer evidence theory.
View Article and Find Full Text PDF