Targeting Peritumoral Lesions Identified by Computed Tomography and Magnetic Resonance Imaging in Feline Injection-Site Sarcomas for Microscopic Examination.

Peritumoral lesions identified during in vivo imaging of feline injection-site sarcoma (FISS) are frequently interpreted as neoplastic. We recently showed that most peritumoral imaging-identified lesions (PTIILs) in FISS are non-neoplastic. In this article, we describe a protocol to target PTIIL for microscopic examination and report on the protocol's performance.

Quantification of surgical margin length changes after excision of feline injection site sarcomas-A pilot study.

Objective: To evaluate degree length change of lateral surgical margins at various stages of processing for histological examination and quantify the length change between grossly normal surgical margins (GNSM) and pathologist-reported histologic tumor-free margin (HTFM) in widely resected feline injection site sarcoma (FISS) specimens.

Study Design: Prospective clinical study.

Animals: Five client-owned cats with injection site sarcomas.

Changes in the dimension and volume of feline injection-site sarcomas following formalin fixation as determined by use of the ellipsoid volume formula and three-dimensional computed tomography software.

OBJECTIVE To evaluate changes in the dimension and volume of feline injection-site sarcomas (FISSs) before (in vivo) and after surgical excision and formalin fixation (ex vivo) as determined by measurements obtained from 2-D and 3-D CT images. SAMPLE 10 excised FISSs. PROCEDURES The maximum length, width, and depth of each FISS were measured on contrast-enhanced 2-D CT images of the tumor obtained in vivo and ex vivo.

Microscopic Evaluation of Peritumoral Lesions of Feline Injection Site Sarcomas Identified by Magnetic Resonance Imaging and Computed Tomography.

Objective: Determine whether dual-phase computed tomography angiogram (CTA) or magnetic resonance imaging (MRI) detect more peritumoral lesions of feline injection site sarcoma (FISS) and determine whether CTA or MRI imaging characteristics of peritumoral lesions correspond with microscopic findings.

Study Design: Prospective clinical study.

Animals: Ten client-owned cats with FISS.

In vitro evaluation of a novel fiducial marker for computed tomography and magnetic resonance imaging of soft tissues in small animals.

Objective: To construct and optimize a fiducial marker suitable for both CT and MRI.

Sample: Fiducial markers containing serial dilutions of iopamidol mixed with water.

Procedures: IV tubing sets were infused with serial dilutions (0% to 100%; increments of 10%) of iopamidol.