Publications by authors named "Jesse L Barnes"
Article Synopsis
- The endocannabinoid system is vital for brain development, particularly in coordinating interactions within neural networks, but existing studies have mostly targeted neuronal differentiation and other isolated processes.
- In developing rodents, the CB1 cannabinoid receptor is primarily found on afferent terminals rather than on output neuron synapses, influencing how synaptic transmission works in the granule cells of the cerebellum.
- Understanding the role of CB1 receptors in the developing cerebellum is crucial, especially with growing discussions around cannabis use, as these receptors affect synaptic strength and network signaling, which has implications for neurodevelopmental disorders.
Exposure to environmental enrichment (EE) reduces sucrose seeking by rats with a history of sucrose self-administration. The present experiment examined whether acute or chronic EE also reduces brain Fos levels, a protein marker indicative of neuronal activation. Fos levels were also examined after either 1 or 30 days of forced abstinence to examine whether Fos levels vary with the incubation of sucrose craving.
View Article and Find Full Text PDFDopamine receptors are implicated in the reinforcing effects of food and drug reinforcement. The purpose of this study was to evaluate whether blocking D2 dopamine receptors during extinction (secondary reinforcement) would affect reacquisition of responding for food pellets (primary reinforcement). Food-restricted rats self-administered (fixed-ratio 1) food pellets in 1-h daily sessions for 7 days.
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