Publications by authors named "Jesse Farruggella"
Behav Brain Res
March 2019
Article Synopsis
- The study investigates how aversive stimuli affect different behaviors—defensive (withdrawal) and appetitive (feeding)—in the mollusk Aplysia, finding that such stimuli enhance withdrawal reflexes while suppressing feeding.
- It highlights that serotonin (5-HT) is responsible for the sensitization (withdrawal enhancement), while nitric oxide (NO) is involved in the suppression of feeding, both in short-term and long-term scenarios.
- The research also uncovers a complex interaction between 5-HT and NO signaling, suggesting that multiple neurotransmitters play a role in modulating behavioral changes after exposure to aversive stimuli.
Neurosci Lett
September 2018
Article Synopsis
- Changes in neuron excitability significantly influence behavior, as demonstrated by the B51 neuron in the mollusk Aplysia, which is part of the feeding neural circuit.
- B51's excitability fluctuates based on external and internal factors, increasing during reward learning (via cAMP) and decreasing with aversive training protocols.
- The study found that cGMP can also reduce B51 excitability, mediated by nitric oxide activation of soluble guanylyl cyclase, highlighting a complex interplay between different cyclic-nucleotide pathways in regulating neuron behavior.
