Publications by authors named "Jesse A Garcia"
Article Synopsis
- The genus Quercus began diversifying about 55 million years ago, resulting in around 450 species, including the California oak Quercus lobata, which has a high-quality genome assembly that showcases its evolutionary advantages.
- Analysis of the oak's genome revealed a large effective population size despite a historical decline, with extensive gene duplications contributing to its genetic and phenotypic diversity.
- Unique patterns of DNA methylation connected to transposable elements indicate a presence of heterochromatin similar to grasses, supporting the idea that these genetic features enhance adaptability to environmental changes.
Evolutionary forces like Hill-Robertson interference and negative epistasis can lead to deleterious mutations being found on distinct haplotypes. However, the extent to which these forces depend on the selection and dominance coefficients of deleterious mutations and shape genome-wide patterns of linkage disequilibrium (LD) in natural populations with complex demographic histories has not been tested. In this study, we first used forward-in-time simulations to predict how negative selection impacts LD.
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