Publications by authors named "Jess Maxwell"
Article Synopsis
- Certain MHC class I alleles, like Mamu-B*08 in rhesus macaques, play a crucial role in controlling HIV and SIV replication.
- In a study of 196 SIV-infected macaques, 38% of elite controllers had the Mamu-B*08 allele, compared to only 3% of progressors.
- Mamu-B*08 was linked to a significant reduction in viral levels during chronic infection, suggesting it could help us understand immune responses in human elite controllers.
