Microalbuminuria, preeclampsia, and preterm delivery in pregnant women with type 1 diabetes: results from a nationwide Danish study.

Objective: To study the association between microalbuminuria and development of preeclampsia and preterm delivery in pregnant women with type 1 diabetes.

Research Design And Methods: This was a population-based prospective study in 846 normoalbuminuric or microalbuminuric women with type 1 diabetes without antihypertensive treatment in early pregnancy. Data were collected prospectively by one to three caregivers in each center and reported to a central registry.

Peri-conceptional A1C and risk of serious adverse pregnancy outcome in 933 women with type 1 diabetes.

Objective: To study the association between peri-conceptional A1C and serious adverse pregnancy outcome (congenital malformations and perinatal mortality).

Research Design And Methods: Prospective data were collected in 933 singleton pregnancies complicated by type 1 diabetes.

Results: The risk of serious adverse outcome at different A1C levels was compared with the background population.

Prenatal risk indicators of a prolonged pregnancy. The Danish Birth Cohort 1998-2001.

Background: Few prenatal risk factors of prolonged pregnancy, a pregnancy of 42 weeks or more, are known. The objective was to examine whether sociodemographic, reproductive, toxicologic, or medical health conditions were associated with the risk of prolonged pregnancy.

Methods: Data from the Danish Birth Cohort in Denmark were used.

Risk factors in developing pregnancy-related pelvic girdle pain.

Background: In this prospective epidemiologic cohort study the aim was to identify possible risk factors for developing four different syndromes of pelvic girdle pain during pregnancy.

Methods: Over a one-year period a total of 2,269 consecutive pregnant women -- at week 33 of gestation -- responded to a structured questionnaire and underwent a thorough physical examination. Women who at baseline reported daily pain from pelvic joints and had corresponding objective findings were allocated, according to symptoms, into one of four classification groups, and followed up with questionnaires and physical examinations up to two years after delivery.

Bacterial vaginosis in early pregnancy is associated with low birth weight and small for gestational age, but not with spontaneous preterm birth: a population-based study on Danish women.

Objective: To analyze the association between bacterial vaginosis (BV) in early pregnancy and preterm birth, low birth weight (LBW) and small for gestational age (SGA) in a Danish population.

Methods: A geographically defined population-based prospective study of Danish-speaking pregnant women over18 years of age enrolled before week 24 and followed until delivery. BV was diagnosed by Amsel's clinical criteria at enrolment.

Outcomes in type 1 diabetic pregnancies: a nationwide, population-based study.

Objective: The aim of this study was to compare pregnancy outcomes in type 1 diabetic pregnancies with the background population.

Research Design And Methods: This nationwide prospective multicenter study took place in eight Danish centers treating pregnant women with type 1 diabetes during 1993-1999. A total of 990 women with 1,218 pregnancies and delivery after 24 weeks (n=1,215) or early termination due to severe congenital malformations (n=3) were included.

Correlation between self-reported gestational age and ultrasound measurements.

Background: We studied the agreement between different measurements of gestational age, i.e. self-reported gestational age in the Danish National Birth Cohort Study, ultrasound-estimated gestational age from the medical records in one Danish county and gestational age from the Danish National Hospital Discharge Register.

Screening for gestational diabetes mellitus by a model based on risk indicators: a prospective study.

Objective: This study was performed to prospectively evaluate a screening model for gestational diabetes mellitus on the basis of clinical risk indicators.

Study Design: In a prospective multicenter study with 5235 consecutive pregnant women, diagnostic testing with a 2-hour 75-g oral glucose tolerance test was routinely performed in women with risk indicators and offered to women without risk indicators as part of the study.

Results: Forty-four percent of the women underwent testing, 43% declined participation, 6% did not speak Danish, and 7% could not be contacted.

Pregnancy outcome and prepregnancy body mass index in 2459 glucose-tolerant Danish women.

Objective: This study was undertaken to investigate the relationship between pregnancy outcome and prepregnancy overweight or obesity in women with a normal glucose tolerance test.

Study Design: A historical cohort study of 2459 pregnant women systematically examined for gestational diabetes was performed. Information of oral glucose tolerance test results and clinical outcome were collected from medical records.

Perinatal and maternal complications related to postterm delivery: a national register-based study, 1978-1993.

Objective: This study was undertaken to estimate the risk of fetal and maternal complications associated with postterm delivery in Denmark.

Study Design: A cross-sectional study that used records from the Danish Medical Birth Registry from 1978 to 1993 was performed. All women with registered prolonged pregnancy (n = 78022) and a 5% random sample of all women who gave birth (n = 47021) were linked to the Danish National Discharge Register.

Audit on stillbirths in women with pregestational type 1 diabetes.

Objective: To audit stillbirth cases in women with type 1 diabetes to search for specific characteristics in order to improve antenatal care and treatment.

Research Design And Methods: Retrospectively identified cases of stillbirths in women with type 1 diabetes during 1990-2000 were analyzed regarding characteristics of the mother, the pregnancy, glycemic control, and the stillborn. The cause of stillbirth was categorized as explainable, likely, or without obvious cause.

Incidence of four syndromes of pregnancy-related pelvic joint pain.

Study Design: A prospective epidemiologic cohort study.

Objective: To determine the incidence of clearly defined pelvic joint pain in pregnancy based on both history and objective confirmation and to classify pelvic joint pain into four groups and determine their incidence.

Summary And Background Data: Pelvic and low back pain in pregnancy is a substantial problem, and the correct treatment is hampered by several factors, such as the lack of clearly defined clinical conditions, variety of nomenclature, and great variance in reported incidence (range 4-76.

Functional ovarian cysts in premenopausal and gynecologically healthy women.

The present study describes 29 women coincidentally found to have ovarian cysts while participating in a cross-sectional study. The prevalence of functional ovarian cysts is determined. In this study, 428 women, aged 14-45 years, were examined by transvaginal ultrasonography.