The level of total sialic acid, alfa-antitrypsin, ceruloplasmin in the serum of patients with choroidal melanoma.

Melanoma of the choroid is a fatal disease because of its metastases. The quest is ongoing for more reliable serum markers for detecting and staging ocular melanoma. Total serum sialic acid and acute phase proteins are valuable adjuncts in the management of malignancies, including melanoma.

The level of alpha-antitrypsin and ceruloplasmin in the subretinal fluid of patients with rhegmatogenous retinal detachment.

Unlabelled: The aim of the study was to determine alpha-antitrypsin (AAT) and ceruloplasmin (CER) level in the subretinal fluid of patients with rhegmatogenous retinal detachment (RRD). Investigation was performed in 41 patients (22 women, 19 men) operated on for RRD at the age from 24 to 81. The group of patients was divided with regard to the extent and duration of RRD.

[Study of mucin layer of tear film in patients with pterygium].

Purpose: The aim of this study was to investigate the tears film, particularly mucin layer in patients with pterygium.

Material And Methods: We examined 31 patients with pterygium--14 women and 17 men. Pterygium in one eye was found in 19 patients, in both eyes in 12.

[Evaluation of the dependence between the lens thickness and intraocular pressure after cataract extraction in patient with glaucoma].

Purpose: The main purpose of the study is the evaluation of the dependence between lens thickness in eyes with cataract and glaucoma and the intraocular pressure after cataract extraction with posterior chamber lens implantation.

Material And Methods: 138 eyes with cataract and glaucoma were examined. Patients were divided into three groups according to the type of glaucoma: I open angle glaucoma II closed angle glaucoma III glaucoma with pseudoexfoliation syndrome All patients received preoperatively drugs reducing intraocular hypertension.

Oral citicoline treatment improves visual pathway function in glaucoma.

Background: Increased latency and reduced amplitude of visual evoked potentials (VEP), frequently encountered in ocular hypertension or open-angle glaucoma, suggest slowed neural conduction in the visual pathways. An improvement in VEP latency and amplitude has been reported following repeated intramuscular injections of citicoline, a neuroprotective drug. Our aim was to find whether citicoline given orally would produce a similar effect.

Citicoline treatment increases retinal dopamine content in rabbits.

Citicoline (exogenous cytidine-5'-diphosphocholine) was reported to enhance dopaminergic neurotransmission in the brain. A few clinical studies showed beneficial effects of this drug on the function of the visual pathway in patients with glaucoma or amblyopia. The present study was aimed at determining whether citicoline could influence retinal catecholamine levels in adult male Albino rabbits.