Glucocorticosteroids (GCS), as the inhibitors of inflammatory reaction in the pleura, may exert a favourable influence on the course of tuberculous pleurisy (TP). GCS applied as an adjuvant therapy to antituberculosis treatment accelerate the regression of symptoms and signs and absorption of pleural fluid in a significant percent of patients. The controlled trials of treatment with GCS failed to show, however, any significant advantages in comparison to placebo with respect to prevention of pleural adhesions or restrictive disturbances of ventilation.
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