Publications by authors named "Jeryl Ritzi T Yu"
Objective: The primary aim of this study is to report long-term outcomes associated with deep brain stimulation (DBS) of the ventral intermediate nucleus (VIM) performed at our institution. We further aimed to elicit the factors associated with loss of efficacy and to discuss the need for exploring and establishing reliable rescue targets.
Methods: To study long-term outcomes, we performed a retrospective chart review and extracted tremor scores of 43 patients who underwent VIM DBS lead implantation for essential tremor at our center.
Individuals with Parkinson's disease (PD) are vulnerable during hospitalizations due to the underlying complexities o1f symptoms, and acute illness or medication changes often lead to decompensation. Complications during hospitalizations are often due to worsening motor and nonmotor symptoms and commonly result from inaccurate medication regimens. Although the accuracy of medication administration relies on an interplay of factors, including patient status, transitions of care, coordination between the hospital prescriber and outpatient neurologist, etc.
View Article and Find Full Text PDFBackground: Towards the end of life (EOL), persons with parkinsonism (PwP) have complex needs and can present with unique palliative care (PC) challenges. There are no widely accepted guidelines to aid neurologists, hospitalists, or PC clinicians in managing the symptoms of PwP at EOL. We examined a population of PwP at EOL, aiming to describe trends of in-hospital management and utilization of PC services.
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- The study looked at how people's Parkinson's disease medications were handled differently when they were treated in the hospital compared to when they took them at home.
- They found that many patients had their medication times messed up or missed doses while in the hospital.
- These problems led to longer hospital stays and higher chances of being readmitted or even passing away soon after leaving the hospital.
Background: Functional Neurologic Disorders (FND) are a common but heterogeneous group of disabling conditions. The Emergency Department (ED) is an important venue for care and referral as it is often the first point of contact when patients with FND are faced with a crisis or exacerbation of symptoms.
Methods: ED providers (n = 273) practicing in the Cleveland Clinic Foundation Northeast Ohio network were invited to participate through secure web application electronic surveys.
Article Synopsis
- This pilot study aimed to identify genetic factors involved in familial Parkinson's disease (PD) among Filipino patients, addressing the unclear prevalence of familial PD.* -
- Eighteen Filipino patients from 11 families underwent genetic evaluation, with testing revealing six individuals carrying mutations associated with PD, particularly in the PINK1 and PRKN genes.* -
- The findings highlight specific genetic mutations linked to early-onset PD, providing foundational data that can support larger future research initiatives, including collaborations like The Global Parkinson's Genetics Program (GP2).*
Article Synopsis
- The study aimed to investigate the prevalence and types of movement disorders in the Philippines, as there is currently no available epidemiologic data on this topic.
- Between 2007 and 2019, 1438 patients were evaluated, revealing that parkinsonism, myoclonus, and tremor were the most common movement disorders, with Parkinson's disease being the leading diagnosis.
- The findings underscore the need for more specialists and dedicated centers in the Philippines to effectively manage the diverse range of movement disorders presented in these specialty clinics.
Background: Although headache is one of the most common neurologic conditions with a high disease burden, primary data on headache research from Southeast Asia (SEA) was hypothesized to be inadequate. This study aimed to evaluate research productivity among the different countries in SEA and to determine the association between specific bibliometric indices and socioeconomic factors.
Methods: A systematic search was conducted until June 10, 2020 in Scopus, PubMed, Embase, Cochrane Central Register of Controlled Trials, and Index Medicus for South-East Asia Region to include all primary headache studies on migraine, tension-type headache, and trigeminal autonomic cephalalgia, with at least one author affiliated with a SEA country.
Background: Hemifacial spasm (HFS) is a chronic, potentially disabling disorder that often requires long-term management with botulinum toxin (BoNT). In a country where healthcare costs limit compliance to medical follow-up and treatment, the study aims to provide a real-world experience on the use of BoNT for HFS among Filipinos.
Methods: We retrospectively collected data from 162 HFS patients who received 1138 botulinum toxin (BoNT) injections from 2006 to 2019 in our movement disorders center in the Philippines.
Article Synopsis
- The COVID-19 pandemic has posed challenges for medical teams managing acute stroke patients, who may not show typical COVID-19 symptoms, making timely intervention essential without sacrificing safety.
- The stroke team evaluated pre-pandemic protocols and identified challenges during the pandemic, leading to the development of a revised acute stroke care algorithm tailored to local resources and practices.
- The new algorithm emphasizes coordination among healthcare professionals, the effective use of personal protective equipment, and the integration of telemedicine, thus improving resource management and stroke care during the pandemic, potentially benefiting other settings with similar limitations.
Background And Purpose: Reversing the effect of dabigatran among patients with atrial fibrillation is important to normalize coagulation profile among patients who develop serious hemorrhage from any source. However, such intervention always has the potential to cause a prothrombotic state. Among patients suspected of ischemic stroke, Idarucizumab, may be administered preceding thrombolysis.
View Article and Find Full Text PDFThe 2019 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which was first reported in Wuhan, China last December 2019, has been declared an emergency by the World Health Organization but eventually progressed to become a Pandemic. To date, Coronavirus Disease 2019 (COVID-19) has affected at least 100,000 individuals worldwide, reaching thousands of mortalities (Zhou et al., 2020; World Health Organization, 2020).
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