Functional characterization of a gene cluster responsible for inositol catabolism associated with hospital-adapted isolates of .

is a nosocomial, multidrug-resistant pathogen. Whole genome sequence studies revealed that hospital-associated isolates are clustered in a separate clade A1. Here, we investigated the distribution, integration site and function of a putative gene cluster that encodes for inositol (MI) catabolism.

Enterococcus faecium genome dynamics during long-term asymptomatic patient gut colonization.

Enterococcus faecium is a gut commensal of humans and animals. In addition, it has recently emerged as an important nosocomial pathogen through the acquisition of genetic elements that confer resistance to antibiotics and virulence. We performed a whole-genome sequencing-based study on 96 multidrug-resistant E.