Publications by authors named "Jersey Heitor Maues"
Investigation of BMP6 mutations in Brazilian patients with iron overload.
Ana Carolina Mourão Toreli Isabella Toni Dulcinéia Martins de Albuquerque Carolina Lanaro Jersey Heitor Maues
Hematol Transfus Cell Ther
November 2024
Article Synopsis
- The study investigates the role of BMP6 mutations in Brazilian patients suffering from iron overload, highlighting that existing HFE gene mutations do not fully account for this condition in diverse populations.
- Researchers evaluated 41 patients and found BMP6 mutations in three individuals, with specific mutations (p.Arg257His and p.Leu71Val) linked to other risk factors like HFE mutations and diabetes.
- The findings suggest that BMP6 mutations could contribute to iron overload when combined with other genetic and clinical factors, indicating a need for further research to clarify BMP6's role in this condition.