Publications by authors named "Jerryl Asin"
Article Synopsis
- Obstructive sleep apnea (OSA) often causes excessive daytime sleepiness (EDS), and pitolisant, a medication that targets histamine receptors, was tested for its efficacy in treating this issue in patients with moderate to severe OSA.
- In a clinical trial with 361 participants, pitolisant was administered in varying doses up to 40 mg daily for 12 weeks, showing a significant reduction in EDS as measured by the Epworth Sleepiness Scale compared to a placebo.
- The study found that pitolisant was well tolerated and improved not only daytime sleepiness but also reaction times and overall patient satisfaction, regardless of whether patients used continuous positive airway pressure (CPAP) therapy.
Bimaxillary osteotomy for obstructive sleep apnoea Objective To gain insight into postoperative results of bimaxillary osteotomy in patients with obstructive sleep apnoea (OSA). Design Retrospective patient series. Method All patients with OSA who had undergone a bimaxillary osteotomy in the Amphia Hospital in Breda in the Netherlands in the past 4 years were eligible for inclusion.
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